Prozone Phenomenon Complicates Detection of Donor Specific Antibodies in Haploidentical Hematopoietic Cell Transplant Patients
نویسندگان
چکیده
منابع مشابه
Rh ANTIBODIES AND THE PROZONE PHENOMENON BY
In 1942 Taylor, Race, Prior, and Ikin reported an anti-Rh serum which failed to agglutinate Rhpositive cells in saline suspension except when diluted. They thought that this prozone was due to antigen and antibody not being present in optimal proportions, and that the mechanism was similar to that of the zones that occur in precipitation reactions. Wiener (1944) described incomplete Rh antibodi...
متن کاملRh antibodies and the prozone phenomenon.
In 1942 Taylor, Race, Prior, and Ikin reported an anti-Rh serum which failed to agglutinate Rhpositive cells in saline suspension except when diluted. They thought that this prozone was due to antigen and antibody not being present in optimal proportions, and that the mechanism was similar to that of the zones that occur in precipitation reactions. Wiener (1944) described incomplete Rh antibodi...
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Prolonged isolated thrombocytopenia (PT) after allogeneic stem cell transplantation (allo-SCT) has a great impact on transplant outcome. In this study, we performed a retrospective analysis to investigate the association of donor-specific anti-human leukocyte antigen (HLA) antibodies (DSAs) with PT in 394 patients who underwent unmanipulated haploidentical blood and marrow transplantation (HBMT...
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Autoimmune hematological diseases (AHDs) occur more frequently than other autoimmune complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and are often refractory to treatment. This study was to analyze the incidence and risk factors of AHDs as well as their response to treatment . Four hundred and forty-five adult malignant hematopoietic disorders underwent allo-H...
متن کامل"No donor"? Consider a haploidentical transplant.
Haploidentical stem cell transplantation (HaploSCT) is an attractive option for patients requiring a hematopoietic stem cell transplant who do not have an HLA-matched donor, because it is cheaper, can be performed faster, and may extend transplantation to virtually all patients in need. Significant advances have been made in the recent decade with dramatic improvement in treatment outcomes. His...
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ژورنال
عنوان ژورنال: Transplantation Research Journal
سال: 2016
ISSN: 2473-1730
DOI: 10.16966/2473-1730.108